Title: Cape Girardeau County Vacation Packages 2026 | Expedia.com [Cape Girardeau County Hotels](https://expedia.com/Destinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations)[Vacation Rentals in Cape Girardeau County](https://expedia.com/Destinations-In-Cape-Girardeau-County.d553248635976430467.Vacation-Rental-Destinations)[Cape Girardeau County Flights](https://expedia.com/Destinations-In-Cape-Girardeau-County.d553248635976430467.Flight-Destinations)[Car Rentals in Cape Girardeau County](https://expedia.com/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Rental-Destinations) ![](https://images.trvl-media.com/place/553248635976430467/cecde210-1fd7-416a-a8df-51b6d814d179.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Cape Girardeau County Vacations & Trips ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ### Your Cape Girardeau County Vacation Travel on your own terms with a vacation package to Cape Girardeau County. Whether you're going for its family-friendly attractions, history, culture, or something else entirely, our package deals make travel planning hassle-free. You can expect to have a to-do list as long as your arm during your trip to Cape Girardeau County. One major city you'll want to spend some time in is [Cape Girardeau](https://www.expedia.com/Cape-Girardeau.d820.Destination-Travel-Guides). Quit dreaming and get packing, because your Cape Girardeau County vacation is only a few clicks away with Expedia. ## Top destinations in Cape Girardeau County ![The Bar - this was one location Gone Girl was filmed at! ](https://mediaim.expedia.com/destination/2/5b27a574bbd8c4a139204e48a625a1c7.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Cape Girardeau [](https://expedia.com/Cape-Girardeau.d820.Destination-Travel-Guides) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248635976430467) ## Find the Best Cape Girardeau County Vacation Packages ## Cape Girardeau County Essential Information | Language | English | | --------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | Currency | U.S dollars | | Closest Airport | Cape Girardeau Municipal Airport (CGI) | | Top Sights | [Cape Rock Park](https://www.expedia.com/Cape-Rock-Park-Cape-Girardeau.d553248621532655781.Vacation-Attraction), [Cape Girardeau Conservation Nature Center](https://www.expedia.com/Cape-Girardeau-Conservation-Nature-Center-Cape-Girardeau.d553248621532655773.Vacation-Attraction) and [Lazy L Safari Park](https://www.expedia.com/Lazy-L-Safari-Park-Cape-Girardeau.d553248621532655782.Vacation-Attraction) | ## Cape Girardeau County Hotel Deals ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel Cape Girardeau Conference Center 3351 Percy Drive Cape Girardeau MO Fully refundableReserve now, pay when you stay $100 nightly $113 total Feb 23 - Feb 24 Total with taxes and fees 9.6/10 Exceptional! (1,003 reviews) Excellent place to stay Reviewed on Feb 19, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F23%2F2026&endDate=2%2F24%2F2026&selected=17269948&PinnedHotelID=17269948&HadPinnedHotel=true®ionId=553248635976430467) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Riverview 777 Main St Cape Girardeau MO Fully refundableReserve now, pay when you stay $94 nightly $107 total Feb 24 - Feb 25 Total with taxes and fees [](https://expedia.com/Hotel-Search?startDate=2%2F24%2F2026&endDate=2%2F25%2F2026&selected=105081384&PinnedHotelID=105081384&HadPinnedHotel=true®ionId=553248635976430467) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Cape Girardeau 3303 Campster Drive Cape Girardeau MO Fully refundableReserve now, pay when you stay $90 nightly $102 total Feb 23 - Feb 24 Total with taxes and fees 9.4/10 Exceptional! (1,003 reviews) Friendly staff, great amneties, spotless, relaxing. We always look for Drurys wherever we go. Reviewed on Feb 15, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F23%2F2026&endDate=2%2F24%2F2026&selected=40831&PinnedHotelID=40831&HadPinnedHotel=true®ionId=553248635976430467) [See all 250 properties in Cape Girardeau County](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=553248635976430467) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf 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![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) Explore a world of travel with Expedia ## Other vacations you might like - Top cities in Cape Girardeau County - Vacations and getaways similar to Cape Girardeau County - Best vacation destinations by month - [Cape Girardeau Vacations ](https://expedia.com/Cape-Girardeau.d820.Destination-Travel-Guides) - [Jackson Vacations ](https://expedia.com/Jackson.d55765.Destination-Travel-Guides) - [Tennessee Vacations ](https://expedia.com/Tennessee.d244.Destination-Travel-Guides) - [Kentucky Vacations ](https://expedia.com/Kentucky.d219.Destination-Travel-Guides) - [Illinois Vacations ](https://expedia.com/Illinois.d215.Destination-Travel-Guides) - [Arkansas Vacations 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Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app